Cul5

ENCODES a protein that exhibits ubiquitin ligase complex scaffold activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN regulation of cytosolic calcium ion concentration; cerebral cortex radially oriented cell migration (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); PARTICIPATES IN neddylation pathway; proteasome degradation pathway involving cullin-dependent ubiquitin ligases; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Brain Injuries; Hemorrhagic Shock; ataxia telangiectasia (ortholog); FOUND IN Cul5-RING ubiquitin ligase complex (ortholog); nucleus (ortholog); site of DNA damage (ortholog); INTERACTS WITH 2,4-dinitrotoluene; acetamide; acrylamide

编码一种展现泛素连接酶复合体支架活性的蛋白质（同源物）；泛素蛋白连接酶结合（同源物）；参与调节细胞质钙离子浓度；大脑皮层径向排列的细胞迁移（同源物）；蛋白酶体介导的泛素依赖性蛋白质降解过程（同源物）；参与 neddylation 途径；涉及 cullin 依赖性泛素连接酶的蛋白酶体降解途径；泛素/蛋白酶体降解途径；与脑损伤、出血性休克相关；与 Ataxia telangiectasia（同源物）相关；存在于 Cul5-RING 泛素连接酶复合体（同源物）中；位于细胞核（同源物）；DNA 损伤位点（同源物）；与 2,4-二硝基甲苯、乙酰胺、丙烯酰胺相互作用。