Mechanisms that specify promoter nucleosome location and identity

The chromatin architecture of eukaryotic gene promoters is generally characterized by a nucleosome-free region (NFR) flanked by at least one H2A.Z variant nucleosome真核生物基因启动子的染色质结构，通常以无核小体区域（nucleosome-free region, NFR）为典型特征，该区域的侧翼至少分布有一个H2A.Z变体核小体。