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Comparative transcriptome of Anabaena (Nostoc) sp. PCC 7120 versus a conditional lethal mutant with silenced furA

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NIAID Data Ecosystem2026-04-25 收录
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The goal of this study is to unveil novel targets of the global regulator FurA using a conditional lethal mutant of Nostoc (Anabaena) sp. PCC 7120. Complete segregation of the inactivated furA gene has not been possible to date. Therefore, comparative transcriptomics of the AGcoaRFurA strain, where furA expression can be silenced and further validation with RT-PCR and EMSA assays of a set of selected genes led to identify novel FurA direct targets involved in different physiological processes.

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2020-01-19
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