Respiratory and intestinal dysbiosis induced by acuter LPS challenge

Systemic inflammatory response syndrome (SIRS) is a severe condition which may lead to multiple organ failure, shock and death. SIRS is often accompanied by intestinal dysbiosis. However, the mechanism, role and details of microbiome alterations during the early phase of acute SIRS are not completely understood. This project characterizes the dynamic alterations of both the respiratory and intestinal microbiome during the early phase of acute SIRS.