The expression of ILT4 on peripheral blood monocytes of sepsis mice at 24 h after CLP was significantly higher (1292.00 ± 143.70 vs. 193.50 ± 52.54, P < 0.05), while the expression of MHC-II on mon
Determine genome-wide open chromatin in P14 memory CD8 T cells 30 days after septic insult Overall design: A small number of naïve P14 CD8 T cells (Thy1.1) were adoptively transferred into congenicall
Determine genome-wide open chromatin in P14 memory CD8 T cells 30 days after septic insult A small number of naïve P14 CD8 T cells (Thy1.1) were adoptively transferred into congenically distinct (Thy1
Sepsis describes the life-threatening systemic inflammatory response (SIRS) of an organism to an infection and is the leading cause of mortality on intensive care units (ICU) worldwide. An acute episo
BackgroundBacterial sepsis is a major threat in neonates born prematurely, and is associated with elevated morbidity and mortality. Little is known on the innate immune response to bacteria among extr