Crystal structure of human Pim-1 kinase in complex with a quinazolinone-pyrrolopyrrolone inhibitor.
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5ipj
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of human Pim-1 kinase in complex with a quinazolinone-pyrrolopyrrolone inhibitor. Descriptor: 2-(tert-butylamino)-3-methyl-8-[(6R)-6-methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4-b]pyrrol-2-yl]quinazolin-4(3H)-one, GLYCEROL, Serine/threonine-protein kinase pim-1 Authors: Mohr, C. Deposit date: 2016-03-09 Release date: 2016-06-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors. J.Med.Chem., 59, 2016
创建时间：
2016-03-09
