Total H3 acetylation in house sparrows

Epigenetic mechanisms are increasingly understood to have major impacts across ecology. However, one molecular epigenetic mechanism, DNA methylation, currently dominates the literature. A second mechanism, histone modification, is likely important to ecologically relevant phenotypes and thus warrants investigation, especially because molecular interplay between methylation and histone acetylation can strongly affect gene expression. There are a limited number of histone acetylation studies on non-model organisms, yet those that exist show that it can impact gene expression and phenotypic plasticity. Wild birds provide an excellent system to investigate histone acetylation, as free-living individuals must rapidly adjust to environmental change. Here, we screen histone acetylation in the house sparrow (Passer domesticus); we studied this species because DNA methylation was important in the spread of this bird globally. This species has one of the broadest geographic distributions in the w..., , , # Total H3 Acetylation in House Sparrows

[https://doi.org/10.5061/dryad.0k6djhb66](https://doi.org/10.5061/dryad.0k6djhb66)

Estimates of total H3 histone acetylation for house sparrows that had been infected with Salmonella.

## Description of the data and file structure

Data are presented for each individual (Bird\_ID) with starting tissue weight, concentration of histone extraction, three replicates of estimate total H3 acetylation, sex, mass (grams), epigenetic potential, and TLR4 gene expression in cecum.

## Sharing/Access information

Data was derived from the following sources:

* house sparrow (*Passer domesticus*)