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Genome-wide measuement of methylated cytosin in regulatory T cells (Treg) and conventional T cells (Tconv) depleted with Uhrf1

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP040997
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To investigate the molecular mechanism how Uhrf1 regulate gene expression and cell cycle progression in Treg, we precipitated methylated DNA using recombinant MBD1 followed by genome-wide analysis of methylated gene loci by next generation sequencer Overall design: Examination of methylated DNA in Treg and Tconv isolated from Cd4cre-Uhrf1+/+ and Cd4cre-Uhrf1flox/flox (Cd4cre-Uhrf1fl/fl)
创建时间:
2017-09-17
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