Role of Cop1 on transcriptional output in 4T1 mouse triple negative breast cancer cells
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https://www.ncbi.nlm.nih.gov/sra/SRP313457
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资源简介：
Cop1 regulates stability of transcription factors. We determined the role of Cop1 in the regulation of Cebpd transciptional output. We generated 4T1breast cancer cells with CRISPR/Cas9 mediated Cop1 (gene symbol RFWD2) knockout. We treated control sgRosa26 and sgCop1 cells with vehicle or IFNgamma (20ng/ml) for 24 hours and isolated RNA for sequencing. Overall design: Examination of transcriptome in Cop1 intact and Cop1 loss 4T1 breast cancer cells in response to IFNgamma.
创建时间：
2021-05-02
