Gene expression profiling of human neuroblastoma cell line SK-N-AS_tetoff_MYCN cultured in the presence (D+) or absence (D-) of 1 µg/ml doxycycline for 6 days. Gene expression profiling of human neuroblastoma cell line SK-N-AS_tetoff_MYCN cultured in the presence (D+) or absence (D-) of 1 µg/ml doxycycline for 6 days

Microarray gene expression profiling reveals that MYCN reprograms cellular metabolism by transcriptional activation of metabolic pathways critical for cancer cell growth and proliferation Overall design: Affymetrix microarray assays were performed according to the manufacturer's directions on total RNA isolated from three independent samples of SK-N-AS_tetoff_MYCN cells cultured in the presence (D+) or absence (D-) of 1 µg/ml doxycycline for 6 days