Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating
Understanding the molecular processes that underlie human phenotypes is one of the great challenges in modern biology. Comparative genomic studies with our closest living evolutionary relatives, chimp
We report the identification of genomic regions bound by RBP2 and JARID2 in mouse cardiomyocytes. RBP2 generates methylated lysine 4 in histone H3. Consistent with previous data, RBP2 binds at the TSS