Log IC50 values for inhibition of nicotinic responses in CN21 and SH-SY5Y cells by the test compounds. Data show mean ± SEM. All values were obtained by best-fit of the Hill-equation as described in t

NIAID Data Ecosystem40

Sox6 Up-Regulation by Macrophage Migration Inhibitory Factor Promotes Survival and Maintenance of Mouse Neural Stem/Progenitor Cells

神经细胞生物学

分子机制

Macrophage migration inhibitory factor (MIF) has important roles in supporting the proliferation and/or survival of murine neural stem/progenitor cells (NSPCs), but downstream effectors remain unknown

NIAID Data Ecosystem30

Brain microglia are maintained and regenerated from a specialized cellular subset. Mus musculus

小胶质细胞

神经细胞生物学

Microglia, macrophages of the brain parenchyma, are essential for normal brain development and function as well as local immune responses. However, they can also induce and perpetuate severe brain pat

NIAID Data Ecosystem50

Proliferation and neural stem cell potential of diencephalic astrocytes revealed by genome-wide expression is SMAd4 dependent – scRNA-seq. Proliferation and neural stem cell potential of diencephalic astrocytes revealed by genome-wide expression is SMAd4 dependent – scRNA-seq

神经细胞生物学

脑区域特异性再生

Neural stem cells (NSCs) have astroglial hallmarks, while astrocytes in the intact adult mammalian brain parenchyma are thought to be postmitotic and lack NSC hallmarks that are activated only after i

NIAID Data Ecosystem30

Comparison of C3 or C3156-181-peptide treated Isolated primary rat neonatal Schwann Cells

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