Summary of the subversion of neutral lipid metabolism in C57BL/6 DLs hosting live L. am amastigotes.

(i) The increased fatty acid (FA) uptake provides a FA pool that, once esterified, could result in TAG accumulation in lipid bodies. (ii) The increased synthesis of CE through cholesterol import and esterification. Thin red and green arrows correspond to transcripts that were up- and down-modulated, respectively. Black arrows correspond to un-modulated pathways. Thick red arrows indicate an increased uptake of key lipid constituents necessary for neutral lipid generation and storage.