OBJECTIVE: To analyze the association between the COVID-19 and olfactory changes, as well as summarize the possible pathophysiological mechanisms involved. METHODS: Integrative literature review, cond
SARS-CoV-2 infection causes a wide spectrum of clinical manifestations in human, and olfactory dysfunction represents as one of the most predictive and common symptoms in COVID-19 patients. However, t
The olfactory system is exposed to external and internal harmful agents that may impair the communication between the olfactory sensory neurons and olfactory brain areas. Inflammatory molecules increa
