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AP-1 family members act at DNA targets in conjunction with Sox9 to promote chondrocyte hypertrophy

ChEBI2016-02-29 更新2026-07-12 收录

软骨细胞分化调控

转录因子协同作用

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-73372 数据链接链接失效反馈

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资源简介：

AP-1 family members act at DNA targets in conjunction with Sox9 to promote chondrocyte hypertrophy

应用场景：

创建时间：

2016-02-29

软骨细胞分化调控

调控网络分析

The growth plate mediates bone growth where SOX9 and GLI factors control chondrocyte proliferation, differentiation and entry into hypertrophy. FOXA factors regulate hypertrophic chondrocyte maturatio

NIAID Data Ecosystem80

Gene expression alteration in chondrocyte by A-CEBP overexpression.

软骨细胞分化调控

转录组功能研究

To investigate loss-of-function of the C/EBP family members, we used A-CEBP which exerts a dominant-negative effect against all CEBPs. DOX-inducible overexpression of A-CEBP into mouse chondrocyte cel

NIAID Data Ecosystem60

Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte [RNA-seq]. Homo sapiens

软骨细胞分化调控

转录因子功能基因组学

We compared Sox9-association at chondrocyte targets to a broad catalogue of regulatory indicators of chromatin organization and transcriptional activity to determine Sox9’s direct regulatory actions i

NIAID Data Ecosystem60

DNA-guided transcription factor cooperativity shapes face and limb mesenchyme [ChIP-seq]

转录因子协同作用

早期胚胎发育

Transcription factors (TFs) can define distinct cellular identities despite nearly identical DNA-binding specificities. One mechanism for achieving regulatory specificity is DNA-guided TF cooperativit

NIAID Data Ecosystem60

Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region

Th2细胞分化

转录因子协同作用

The T helper type 2 (Th2) locus control region (LCR) regulates Th2 cell differentiation. Several transcription factors bind to the LCR to modulate the expression of Th2 cytokine genes, but the molecul

NIAID Data Ecosystem60

AP-1 family members act at DNA targets in conjunction with Sox9 to promote chondrocyte hypertrophy

资源简介：

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