Cis-regulatory evolution in primates - ChIP-seq

Cis-regulatory evolution has played a critical role in shaping animal and plant phenotypic diversity. We include data of five primate species (excluding human samples) used to study the evolution of promoters and enhancers in the livers of six species selected from all major clades of the primate lineage. We produced ChIP-seq data for two different histone modifications to profile active and poised regulatory elements, and performed RNA-seq on the same samples to produce corresponding transcriptional profiles.