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Nlrp12-defecient hematopoietic cells caused intestinal dysbiosis via increased proinflammatory cytokines. 16s rRNA sequence from mice commensal

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NIAID Data Ecosystem2026-03-10 收录
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In order to identify which cell components cause the dysbiotic microbiome in the Nlrp12-defecient mice, we performed the 16s rRNA sequencing of fecal DNA isolated from wild type and Nlrp12-defecient mice receiving bone marrow cell expressing NLRP12 or not. We also compared the microbiome difference after neutralizing antibodies target TNF (Infliximab) and IL6r (tocilizumab).

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2016-12-19
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