Case-control based association of chromosome 9p21 with CAD.

Ordinary logistic regression in an additive model was calculated for combined subsets of CAD adjusted to major risk factors of atherosclerosis (age, gender, smoking, diabetes, HDL-C- and LDL-C-levels adjusted for statin treatment). Analyses of myocardial infarction were only adjusted for age, gender, smoking, diabetes, but not for HDL-C and LDL-C, because the latter parameters significantly change during the acute event. ORs are given per allele.