NEW EMBO MEMBER’S REVIEW
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NEW EMBO MEMBER’S REVIEW
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2002-07-15
相关数据集
PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
The p85-associated phosphatidylinositol (PI) 3-kinase/Akt pathway mediates the oestradiol-induced S-phase entry and cyclin D1 promoter activity in MCF-7 cells. Experiments with Src, p85α and Akt domin
PubMed Central2001-11-01 更新510
Modulation of DNA repair by mutations flanking the DNA channel through RNA polymerase
The RuvABC and RecBCD proteins promote rescue of stalled or broken DNA replication forks in Escherichia coli. Strains lacking these proteins cope poorly with DNA damage and have problems with chromoso
PubMed Central2002-12-16 更新20
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication
Budding yeast Mps1p kinase has been implicated in both the duplication of microtubule-organizing centers and the spindle assembly checkpoint. Here we show that hMps1, the human homolog of yeast Mps1p,
PubMed Central2002-04-02 更新20
Central role of Drosophila SU(VAR)3–9 in histone H3-K9 methylation and heterochromatic gene silencing
Su(var)3–9 is a dominant modifier of heterochromatin-induced gene silencing. Like its mammalian and Schizosaccharomyces pombe homologues, Su(var) 3–9 encodes a histone methyltransferase (HMTase), whic
PubMed Central2002-03-01 更新40
A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling
Ligand-induced desensitization of the epidermal growth factor receptor (EGFR) is controlled by c-Cbl, a ubiquitin ligase that binds multiple signaling proteins, including the Grb2 adaptor. Consistent
PubMed Central2002-02-01 更新20



