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Human Cytochrome P450 17A1 in complex with inhibitor: abiraterone C6 nitrile

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6ciz
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Human Cytochrome P450 17A1 in complex with inhibitor: abiraterone C6 nitrile Descriptor: 6-cyano-17-(3-pyridyl)-androst-5,16-dien-3-ol, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase Authors: Scott, E.E, Fehl, C. Deposit date: 2018-02-25 Release date: 2018-06-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.601 Å) Cite: Structure-Based Design of Inhibitors with Improved Selectivity for Steroidogenic Cytochrome P450 17A1 over Cytochrome P450 21A2. J. Med. Chem., 61, 2018
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2018-02-25
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