AF3 models of virus-virus, virus-host and host-host dimers from HSV-1 infected cells.
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PPIs were uncovered by chemical cross-linking of intact HSV-1 infected cells at 24hpi with DSSO. Hetero-dimeric PPIs were additionally predicted by AlphaFold3 v.3.0.1 <sup>9</sup> on a local workstation utilizing an NVIDIA RTX A6000. Structure prediction was done in a docker environment with default parameters for protein-protein sequences generating 5 predicted models through 1 random seed, model parameters were provided by Google Deepmind.
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Bogdanow, Boris创建时间：
2025-05-16
