Crystal structure of HIV protease model precursor/Darunavir complex
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Crystal structure of HIV protease model precursor/Darunavir complex Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, GLYCEROL, ... Authors: Agniswamy, J, Sayer, J, Weber, I, Louis, J. Deposit date: 2011-08-29 Release date: 2012-04-25 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Terminal interface conformations modulate dimer stability prior to amino terminal autoprocessing of HIV-1 protease. Biochemistry, 51, 2012
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2011-08-29
