SPINOL-Derived Phosphoric Acids: Synthesis and Application in Enantioselective Friedel−Crafts Reaction of Indoles with Imines
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https://figshare.com/articles/dataset/SPINOL_Derived_Phosphoric_Acids_Synthesis_and_Application_in_Enantioselective_Friedel_Crafts_Reaction_of_Indoles_with_Imines/2703796
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资源简介：
A new class of chiral phosphoric acids with spirobiindane as scaffold were conveniently synthesized from (S)-1,1′-spirobiindane-7,7′-diol ((S)-SPINOL) and employed to catalyze the asymmetric Friedel−Crafts reaction of indoles with imines to afford 3-indolyl methanamines. High yields (68−97%) and excellent enantioselectivities (up to 99% ee) were obtained.
创建时间：
2010-12-17
