Additional file 3: of The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
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Sheet 1: Detailed information on the copy number alterations detected in the MCF-7 cell sub-lines. Sheet 2: Detailed information on the copy number alterations detected in the MDA-MB-231 cell sub-lines. Sheet 3: A list of genes in which copy number alterations were detected in the MCF-7 cell sub-lines. A ‘1’ denotes that a CNA is detected in a given stage (sub-line). A ‘0’ indicates that it was not observed. Information on any alterations in expression observed for a gene with a CNA in the final stage (MCF-7RES-65nM) is given in last columns. Sheet 4: Similar to sheet 3, but with data for the MDA-MB-231 sub-lines. Sheet 5: Similar to sheet 3 but here showing only those genes in which a CNA has been detected in a given stage (sub-line) of MCF-7 and where the expression of the gene was altered in the final stage (MCF-7RES-65nM). Sheet 6: Similar to sheet 5, but with data for the MDA-MB-231 sub-lines. Sheet 7: Overview of the approximate regions in which copy numbers were detected in the MCF-7 cell sub-lines. Sheet 8: Similar to sheet 7, but with data for the MDA-MB-231 sub-lines. (XLSX 1399 kb)



