Effects of imidazo[1,2-a]pyridine-N-glycinyl-hydrazone derivatives 1a–k on TNF-α production and cell viability in murine peritoneal macrophages.
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The results are expressed as the apercent inhibition and bpercent cell viability compared to the vehicle (DMSO); n = 3 independent experiments performed in duplicate;*p = 0.05 using student’s t test; cIC50 values were determined using at least five concentrations, the range concentration are showed in parentheses; d SI = cytotoxicity IC50/anti-TNF-α IC50; e values calculated using ACDLABS software.
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2015-12-02
