THE INFLUENCE OF NUTRITION ON THE FORMATION OF PANS ENZYME SECRETION AND HOMEOSTASIS OF MICE OF DIFFERENT AGES IN POSTNATAL ONTOGENESIS

The purpose of the study is to study the influence of nutrition on the formation of pancreatic enzyme secretion and homeostasis in rats of different ages. Experiments were conducted on white, outbred, male rats of different ages (15 days, 1 month, 1.5 months, 2 months, 3 months, and 4 months) in the institute's vivarium. The amylolytic and lipolytic activity of pancreatic homogenate and blood in rats was studied. According to the obtained results, the intensity of the increase in the amylolytic activity of pancreatic tissue was higher with age in rats. In young rats, the level of amylolytic enzyme incorporation into the blood was higher than in adult rats. It was observed that the lipolytic activity of the rats under our observation increases uniformly to a certain extent with each age. In rats fed protein-rich food, the formation of the activity of both enzymes (amylase, lipase) in postnatal ontogenesis accelerated.