PREECLAMPSIA DURING PREGNANCY AND ITS NEPHROLOGICAL COMPLICATIONS

The following article investigates the kidney-related issues that arise from preeclampsia during pregnancy because this condition represents a severe threat to both maternal and fetal well-being. The medical condition known as preeclampsia develops when pregnant individuals develop increased blood pressure together with protein in their urine after the 20th week of their pregnancy. The disease state may lead to damage of multiple entire body systems with renal failure emerging as a particularly severe manifestation. Medical professionals at the Multidisciplinary Clinic of Samarkand State Medical University in Uzbekistan reviewed preeclampsia cases from 150 pregnant patients between 2022 and 2024. A study objective examined the occurrence patterns alongside organ damage levels for nephrological conditions including proteinuria together with elevated serum creatinine degree and glomerular filtration rate reductions and acute kidney injury manifestations. The research indicated that moderate to severe proteinuria manifestation occurred in 63% of patients while elevated serum creatinine levels were seen in 22% of the subjects and 11% of cases showed acute kidney injury symptoms. Renal impairment severity showed a direct correlation with both hypertension intensity and the time when prenatal hypertension was first diagnosed. People who received swift intervention through quick diagnosis presented superior outcomes for maternal and newborn health. The article demonstrates that pregnant women at risk for preeclampsia should receive continuous renal function monitoring during their pregnancy. Future studies must investigate the development of early biomarkers for renal impairment since these biomarkers could help prevent neurodevelopmental issues in both mothers and their newborns. Keywords: Preeclampsia, pregnancy complications, nephrology, proteinuria, renal dysfunction, acute kidney injury, maternal health, hypertension, Uzbekistan, prenatal care