Structure of full-length LRRK2 bound to MLi-2 (I2020T mutant)
收藏Protein Data Bank Japan2024-12-25 更新2026-04-19 收录
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Structure of full-length LRRK2 bound to MLi-2 (I2020T mutant) Descriptor: (2~{R},6~{S})-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1~{H}-indazol-3-yl]pyrimidin-4-yl]morpholine, E11 DARPin, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Sanz-Murillo, M, Villagran-Suarez, A, Alegrio Louro, J, Leschziner, A. Deposit date: 2023-08-26 Release date: 2023-12-06 Last modified: 2024-12-25 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures. Sci Adv, 9, 2023
创建时间：
2023-08-26
