Human Cytochrome P450 2D6 BACE1 Inhibitor 6 Complex
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4xrz
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Human Cytochrome P450 2D6 BACE1 Inhibitor 6 Complex Descriptor: (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(1H-pyrazol-4-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, Cytochrome P450 2D6, GLYCEROL, ... Authors: Johnson, E.F, Fan, Y. Deposit date: 2015-01-21 Release date: 2015-05-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug-Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors. J.Med.Chem., 58, 2015
创建时间：
2015-01-21
