EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq]
收藏官方服务:
资源简介:
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq]
应用场景:
创建时间:
2015-11-02
相关数据集
The Paramecium Ezl1 protein mediates dual methylation of H3 lysines 9 and 27
The goal of the present project was to determine which Paramecium histone H3 residues are methylated in an Ezl1-dependent manner.
NIAID Data Ecosystem80
The polycomb protein Ezh2 regulates differentiation and plasticity of CD4 T helper type-1 and type-2 cells.. Mus musculus
Following antigen encounter by CD4 T cells, polarizing cytokines induce the expression of master regulators that control differentiation. Inactivation of the histone methyltransferase Ezh2 was found t
NIAID Data Ecosystem40
The crystal structure of methyltransferase domain of human SET domain-containing protein 2 in complex with S-adenosyl-L-homocysteine
The crystal structure of methyltransferase domain of human SET domain-containing protein 2 in complex with S-adenosyl-L-homocysteine Descriptor: CHLORIDE ION, Histone-lysine N-methyltransferase SETD2,
Protein Data Bank Japan2023-09-13 更新30
Demethylation of the protein phosphatase PP2A promotes demethylation of histones to enable their function as a methyl group sink
Dysregulation of chromatin methylation is associated with defects in cellular differentiation as well as a variety of cancers. How cells regulate the opposing activities of histone methyltransferase a
NIAID Data Ecosystem50
ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression [RNA-Seq]
Metazoan transcription factors typically regulate large numbers of genes. Here we identify via a CRISPR-Cas9 genetic screen ZNF410, a pentadactyl DNA binding protein that in human erythroid cells dire
NIAID Data Ecosystem30



