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DNA methylation sequence of MJD mice cerebellum

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NIAID Data Ecosystem2026-03-13 收录
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DNA methylation has recently been linked to transcriptional dysregulation and neuronal dysfunction in polyglutamine (polyQ) disease. This study aims to determine whether (CAG)n expansion in ATXN3 perturbs DNA methylation status. We analyzed DNA methylation throughout the genome using reduced representation bisulfite sequencing (RRBS).

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2022-09-01
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