Gldc

ENCODES a protein that exhibits enzyme binding; glycine binding; glycine dehydrogenase (decarboxylating) activity; INVOLVED IN glycine decarboxylation via glycine cleavage system; protein-containing complex assembly; cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; folate cycle metabolic pathway; ASSOCIATED WITH chromosome 9p deletion syndrome (ortholog); COVID-19 (ortholog); Developmental Disabilities (ortholog); FOUND IN glycine cleavage complex; mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 3-chloropropane-1,2-diol

编码一种表现出酶结合、甘氨酸结合、甘氨酸脱氢酶（脱羧）活性特性的蛋白质；参与甘氨酸脱羧反应，通过甘氨酸裂解系统实现；参与蛋白复合物组装；对白血病抑制因子的细胞反应（同源）；参与二氢嘧啶脱氢酶缺乏途径、二甲基甘氨酸脱氢酶缺乏途径、叶酸循环代谢途径；与9p染色体缺失综合征（同源）、COVID-19（同源）、发育障碍（同源）相关；存在于甘氨酸裂解复合物、线粒体（同源）、核质（同源）中；与1,2-二甲基肼、17β-雌二醇、3-氯丙烷-1,2-二醇相互作用。