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Crystal structure of cMET in complex with novel inhibitor

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Crystal structure of cMET in complex with novel inhibitor Descriptor: Hepatocyte growth factor receptor, N-(3-nitrobenzyl)-6-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4-amine Authors: Liu, Q.F, Chen, T.T, Xu, Y.C. Deposit date: 2012-08-06 Release date: 2012-10-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: Synthesis and SAR study as tyrosine kinase c-Met inhibitors. Bioorg.Med.Chem.Lett., 22, 2012

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2012-08-06
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