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NKG2A educates uterine NK cells to optimise pregnancy outcomes in humans and mice

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP316705
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资源简介:
We report abnormal pregnancy outcomes in mice lacking NKG2A, including altered placental transcription. In humans, we find HLAB-21T snp to be associated with an increased risk of pre-eclampsia. Overall design: We compared placental mRNA expression at E15.5 in genetically-matched fetuses who were closest to their litter mean weight, from Klrc1-/- and C57BL/6 dams. Samples were run in 2 batches, with a SAVANT correction for batch effect.
创建时间:
2021-04-30
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