NADE modulates death signalling
收藏reactome.org2025-01-09 收录
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NADE protein (p75NTR-associated cell death executor) may induce cell death upon NGF binding, but not BDNF, NT3, or NT4/5 binding, to p75NTR. The NADE-dependent apoptosis is modulated by the 14-3-3-epsilon protein (Kimura MT et al, 2001).
NADE蛋白(p75NTR相关细胞死亡执行者)在NGF结合时可能诱导细胞死亡,然而,并非BDNF、NT3或NT4/5与p75NTR结合时。依赖NADE的细胞凋亡过程受到14-3-3-epsilon蛋白(Kimura MT 等人,2001年)的调节。
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