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Bivalent Chromatin Marks Developmental Regulatory Genes in the Mouse Embryonic Germline in Vivo. Mus musculus

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NIAID Data Ecosystem2026-03-07 收录
下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA199926
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资源简介:
We developed a ChIP protocol for the analysis of histone marks using less than 10,000 cells per IP, and used it to investigate the chromatin state of E11.5 mouse primordial germ cells (PGCs). A genome-wide ChIP-Seq analysis of E11.5 PGCs revealed a distribution of H3K4me3/H3K27me3 bivalent domains highly enriched for developmental regulatory genes. Overall design: H3K4me3 and H3K27me3 ChIP-Seq from mouse E11.5 primordial germ cells.
创建时间:
2013-04-25
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