Asymmetric One-Pot Sequential Mannich/Hydroamination Reaction by Organo- and Gold Catalysts: Synthesis of Spiro[pyrrolidin-3,2′-oxindole] Derivatives
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https://figshare.com/articles/dataset/Asymmetric_One_Pot_Sequential_Mannich_Hydroamination_Reaction_by_Organo_and_Gold_Catalysts_Synthesis_of_Spiro_pyrrolidin_3_2_oxindole_Derivatives/2422663
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An asymmetric organo- and gold-catalyzed one-pot sequential Mannich/hydroamination reaction has been developed. Using this protocol, spiro[pyrrolidin-3,2′-oxindole] derivatives were synthesized in good yields (up to 91%) and excellent enantioselectivities (up to 97% ee).
创建时间:
2016-02-19



