CLK3 A319V mutant bound with benzothiazole Tg003 (Cpd 2)
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CLK3 A319V mutant bound with benzothiazole Tg003 (Cpd 2) Descriptor: (1~{Z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one, 1,2-ETHANEDIOL, Dual specificity protein kinase CLK3 Authors: Schroeder, M, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2020-04-24 Release date: 2020-07-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.76 Å) Cite: DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity. J.Med.Chem., 63, 2020
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2020-04-24
