Transcriptome sequencing analysis of GADD45B and HOPX gene overexpression in human cutaneous melanoma

We first overexpressed two genes, GADD45B and HOPX, in human malignant melanoma cells A375 cells, and then performed transcriptome sequencing. The related differential gene expression and the alteration of related signaling pathways were obtained by comparing with the control group. This study provides a reference and basis for the treatment of human melanoma. Examination of downstream gene expression and intrinsic mechanisms following overexpression of two genes in human malignant melanoma.