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Altered BAF53A (ACTL6A) Stoichiometry Drives Human Squamous Cell Carcinoma [CnR]

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NIAID Data Ecosystem2026-03-13 收录
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To determine whether the chromatin accessibility for YAP/TEADs in squamous cell carcinoma cells is directly regulated by BAF53A within BAF complexes, we performed CUT&RUN to profile the distribution of YAP, TEAD1, and BAF155 (a DNA binding subunit of BAF complexes) across the genome. The CUT&RUN experiments were conducted 72 hours after siRNA transfection or one week after lentivirus transduction and drug selection. Two samples for each condition.

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2022-01-28
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