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Using ICP detect somatic HDR
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2023-06-07
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Appendix S1 - A Stochastic Model of DNA Fragments Rejoining
Mathematical details related to the model development and numerical solutions to the model described. (PDF)
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Kinetics and fidelity of the repair of Cas9-induced double-strand DNA breaks. Brinkman, E.K. et al
Figure 1: We established a clonal K562 cell line with a stably integrated construct that encodes a tightly controlled inducible Cas9 nuclease. Western blot analysis of Cas9 at various time points afte
Mendeley Data2024-06-25 更新30
“Gate-keeper” Residues and Active-Site Rearrangements in DNA Polymerase μ Help Discriminate Non-cognate Nucleotides
Incorporating the cognate instead of non-cognate substrates is crucial for DNA polymerase function. Here we analyze molecular dynamics simulations of DNA polymerase μ (pol μ) bound to different non-co
Figshare2016-01-18 更新10
Robustness of DNA Repair through Collective Rate Control
DNA repair and other chromatin-associated processes are carried out by enzymatic macromolecular complexes that assemble at specific sites on the chromatin fiber. How the rate of these molecular machin
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Kinetics and fidelity of the repair of Cas9-induced double-strand DNA breaks. Brinkman, E.K. et al
Figure 1: We established a clonal K562 cell line with a stably integrated construct that encodes a tightly controlled inducible Cas9 nuclease. Western blot analysis of Cas9 at various time points afte
Mendeley Data2018-01-01 更新20
