Crystal structure of human Trap1 with DN203495
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Crystal structure of human Trap1 with DN203495 Descriptor: 1-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-4-chloranyl-pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial Authors: Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C. Deposit date: 2020-04-30 Release date: 2020-07-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models. Bioorg.Chem., 101, 2020
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2020-04-30
