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Running and locomotor plasticity

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NIAID Data Ecosystem2026-03-10 收录
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In precious studies, we established an animal model with the genetic absence of the CST by conditionally inactivating Celsr3 in corticospinal motor neurons (Emx1-Cre;Celsr3f/- mice) and found that spontaneous plasticity of the motor network partially contributed to functional recovery.However, Emx1-Cre;Celsr3f/- mice still behave movement abnormalities compared to the littermate control. In this study, we assess whether voluntary exercise fosters functional improvement and its potential mechanisms.

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2019-02-09
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