Additional file 15 of HBV-driven host chromatin accessibility changes affect liver metabolic pathways, iron homeostasis and promote a preneoplastic phenotype
We employed a highly sensitive technology, 3C-HTGTS (3C-high-throughput genome-wide sequencing), to globally identify HBV DNA-host DNA contacts in cellular models of HBV infection. We found that HBV
Gene expression profile at single nucleus level of liver cells from the healthy and diseased donors Overall design: Single nucleus RNA-sequencing of normal and diseased liver
Acute liver injury (ALI) is a severe clinical condition that can progress to chronic liver failure, cirrhosis, or hepatocellular carcinoma, yet current therapeutic options remain limited and outcomes