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BACE-1 in complex with ELN475957

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Protein Data Bank Japan2024-11-27 更新2026-03-21 收录
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BACE-1 in complex with ELN475957 Descriptor: Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide Authors: Probst, G.D, Bowers, S, Sealy, J.M, Brecht, E, Yao, N. Deposit date: 2010-07-01 Release date: 2010-09-22 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region. Bioorg.Med.Chem.Lett., 20, 2010

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2010-07-01
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