Weak Brønsted Acid−Thiourea Co-catalysis: Enantioselective, Catalytic Protio-Pictet−Spengler Reactions
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https://figshare.com/articles/dataset/Weak_Br_nsted_Acid_Thiourea_Co_catalysis_Enantioselective_Catalytic_Protio_Pictet_Spengler_Reactions/2877382
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资源简介：
The development of one-pot imine formation and asymmetric Pictet−Spengler reactions cocatalyzed by a chiral thiourea and benzoic acid is described. Optically active tetrahydro-β-carbolines, ubiquitous structural motifs in biologically active natural products, are obtained in high ee directly from tryptamine and aldehyde precursors.
创建时间：
2016-02-26
