官方服务:
资源简介:
Fetal sheep hepatocytes were treated for 24h with metformin Overall design: Fetal sheep hepatocytes were treated for 24h with metformin
应用场景:
创建时间:
2023-02-07
相关数据集
Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons
Metformin is a widely prescribed drug used to treat type-2 diabetes, although recent studies show it has wide ranging effects to treat other diseases. Animal and retrospective human studies indicate t
NIAID Data Ecosystem80
The effect on the transcriptome by inhibition of mitochondrial function by metformin in intestinal cells
We purified mouse duodenal cells from organoids derived from two different transgenic mouse lines (GIP-Cre tdRFP, SST-Cre tdRFP), and identified transcripts enriched in metformin-treated cells. Compar
NIAID Data Ecosystem30
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts
We report the effects of metformin treatment on the transcriptome of normal human dermal fibroblasts isolated from foreskin (designated 2DD). We sequenced mRNA from 2 replicates of proliferative (PRO)
NIAID Data Ecosystem20
Metformin Regulates Metabolic and Non-Metabolic Pathways in Skeletal Muscle and Subcutaneous Adipose Tissues of Older Adults. Metformin Regulates Metabolic and Non-Metabolic Pathways in Skeletal Muscle and Subcutaneous Adipose Tissues of Older Adults
Administration of metformin increases healthspan and lifespan in model systems and evidence from clinical trials and observational studies suggests that metformin delays a variety of age-related morbi
NIAID Data Ecosystem60
Importance of AMPK in metformin suppression of liver glucose production
Metformin is now the most widely prescribed oral anti-diabetic agent worldwide, taken by over 150 million people annually. Although metformin has been used clinically to treat type 2 diabetes for over
NIAID Data Ecosystem30



