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A TBK1-independent primordial function of STING in lysosomal biogenesis. Bo Lv et al

Name: A TBK1-independent primordial function of STING in lysosomal biogenesis. Bo Lv et al
Creator: University of Pittsburgh; University of Minnesota
Published: 2026-04-09T12:26:12+08:00

Mendeley Data2026-04-09 收录

溶酶体生物发生

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Raw data for Western blot, microscope images, and bar plots in the paper "A TBK1-independent primordial function of STING in lysosomal biogenesis" published on Molecular Cell.

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University of Pittsburgh; University of Minnesota

蛋白质晶体

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Crystal structure of human cGAS apo form Descriptor: Cyclic GMP-AMP synthase, ZINC ION Authors: Kato, K, Ishii, R, Ishitani, R, Nureki, O. Deposit date: 2013-09-05 Release date: 2013-10-30 Last modifi

Protein Data Bank Japan2023-11-08 更新70

Gp130-dependent release of acute phase proteins is linked to the activation of innate immune signaling pathways

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细胞基因调控

Gp130 dependent gene expression was analyzed in a previously established hepatocyte-specific gp130-knockout mouse model. Whole transcriptome analysis for isolated hepatocytes was performed to measure

NIAID Data Ecosystem50

Gene expression in HeLa cells expressing GFP-IRF3 (non-targeting control and clonal knockouts of DDX58, MAVS, ATP13A1, CAPN15, TADA2B, MED16, and MED24) following Sendai virus (SeV) infection or hpRNA transfection. Gene expression in HeLa cells expressing GFP-IRF3 (non-targeting control and clonal knockouts of DDX58, MAVS, ATP13A1, CAPN15, TADA2B, MED16, and MED24) following Sendai virus (SeV) infection or hpRNA transfection

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CRISPR基因功能筛选

IRF3 translocates from the cytoplasm to the nucleus upon recognition of a cytoplasmic RNA stimulus by RIG-I or MDA5. Using an optical pooled CRISPR knockout screen in HeLa-Cas9 cells, we identified AT

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Mechanisms Establishing TLR4-Responsive Activation States of Inflammatory Response Genes

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炎症与表观遗传调控

Precise control of the innate immune response is required for resistance to microbial infections and maintenance of normal tissue homeostasis. Because this response involves coordinate regulation of h

NIAID Data Ecosystem60

Structure of apo-SPO1 Tad2

蛋白质结构解析

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Structure of apo-SPO1 Tad2 Descriptor: Gp34.65 Authors: Xiao, Y, Feng, Y. Deposit date: 2023-09-25 Release date: 2024-09-25 Last modified: 2024-12-04 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Single ph

Protein Data Bank Japan2024-12-04 更新50

A TBK1-independent primordial function of STING in lysosomal biogenesis. Bo Lv et al

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