Therapeutic responses and PCR-corrected outcomes by treatment regimen.

All data are number [%(95% CI)] unless otherwise indicated; CIs are based on binomial (exact) calculations; p-values are for Fisher’s exact test. *Wilcoxon test was used for comparing parasite and fever clearance times. ¥Vivax recurrence in those with initial vivax infection. €Falciparum recurrences in volunteers with initial falciparum or mixed infections (n = 2 in each arm) were all true recrudescences by PCR. One subject with initial falciparum infection developed vivax infection at Day 42 and was counted as failure in the all-species analysis only. *PP analysis excludes subjects withdrawn or lost-to-follow-up. **ITT analysis treats subjects withdrawn or lost-to-follow-up as treatment failures. ***Mean (median) follow-up duration 102 days (115 days).