HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation

To investigate the effect of HMGA1 in pancreatic cancer. Here we established E3LZ10.7 cell lines in which HMGA1 has been knocked down by shRNA. We then performed gene expression profiling analysis using data obtained from RNA-seq Overall design: Comparative gene expression profiling analysis of RNA-seq data for E3LZ10.7 cells with or without HMGA1 silencing